Neogene Therapeutics is a global, clinical-stage biotechnology company pioneering the discovery, development, and manufacturing of next-generation engineered T cell receptor (TCR) therapies targeting a broad spectrum of solid cancers.

Cancer is a genetically individual disease – no two tumors are exactly the same. Genetic changes can create neoantigens – unique targets in or on tumor cells that set them apart from healthy cells. Neogene’s novel approach delivers a tailored therapy based on neoantigen-targeting TCR genes that target neoantigens found in an individual patient’s tumor. Our proprietary TCR identification and selection platform allows us to identify neoantigen-specific TCR genes. These TCR genes are engineered into patient-derived T cells based on in-house developed T cell engineering technologies with the goal of eliciting strong and durable responses in a variety of solid tumor indications. The ability of such engineered T cells to attack a patient tumor can be further modulated through additional, targeted genetic modifications that are explored by Neogene for this purpose.

By developing a portfolio of TCRs targeting common cancer-causing mutations that result in neoantigens shared between patients as well as TCR therapies targeting neoantigens unique to a patient’s tumor, we aim to enable wider access to individualized engineered T cell therapies for a broad spectrum of cancers.

OUR MISSION
Pioneering next-generation, neoantigen-targeting engineered T cell receptor therapies for solid cancers

Our Values

• BOLD: We are bold in thought and action and committed to innovation in all we do.
• HUMBLE: We roll up our sleeves to get the job done and leave no room for egos.
• RESPECTFUL: We prioritize kind directness and ensure every voice counts.
• COHESIVE: We look out for each other as we work hard because how we work together drives our success.

Join Our Team

We offer the opportunity to join a highly dynamic, global clinical-stage biotechnology company. You can expect a collaborative environment created by a team with deep scientific expertise and an industrial track-record in T cell therapies. We value pro-active team-players who pursue their goals with dedication, endurance and a daring mindset. If you share our commitment to make a difference to patients in need, we can provide an exciting opportunity for your career.